The study was funded in part by the 10.13039/100010661Horizon 2020 grant ImmunoSep (847422) and in part by the Hellenic Institute for the Study of Sepsis. M.G.N. is supported by an 10.13039/501100000781ERC Advanced Grant (833247) and a Spinoza grant of the 10.13039/501100003246Netherlands Organization for Scientific Research.