1  Introduction
Dear Sir,
The pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global threat to public health [1]. SARS-COV-2 is a single-strand RNA virus with 96.3% sequence identity the bat coronavirus RaTG13 [[2], [3], [4]]. The spike protein of SARS-COV-2 is responsible for entry of the host cells via binding to surface angiotensin converting enzyme 2 [2,5]. The estimated mortality rate for COVID-19 is about 2.3%, with a range of 6 to 41 days from the onset of symptoms to death [6,7]. The prominent pathological changes in lungs include edema, proteinaceous exudate, and multinucleated pneumocytes [8,9]. We here first report the lipid pathophysiology in COVID-19.