At present, there is no mention of changes on eosinophils in the latest diagnosis and treatment plan released by the Chinese government. With the increase of the COVID-19 research, we have seen some reports of eosinopenia [10]. However, compared with the published literature, our study found that the proportion of eosinophil changes was higher, among which 21 (66%) and 24 (75%) patients showed a decrease in eosinophil count and proportion. This may be related to our research object is the COVID-19 screening patients, these patients are in the early stage of the disease, the body's emergency response is more intense, so the decline of eosinophils is faster. But, the relationship between eosinophils and disease severity needs further study.