Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System
JACC Review Topic of the Week

Abstract
Severe acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2