Hypersynchronous neuronal activity is the defining feature of epileptic seizures, and almost all of our strategies for recording ictal brain states focus on identifying signatures of this neuronal dysfunction. But it is not all about the neurons: astrocytes have recently achieved due recognition as more than just “support crew” for the more flashy neurons; they actively participate in brain homeostasis, signal processing, and dynamic regulation of brain states.1 And as Diaz Verdugo and colleagues elegantly demonstrate in zebrafish, a gap junction coupled network of astrocytes also seems to play a key role in the ictogenesis of generalized seizures.