iological features (CR model) were developed. ROC analyses for the primary and validation cohort are shown in Table 4 and Fig. 3. The CR model yielded a maximum AUC of 0.986 (95% CI 0.966~1.000) in the primary cohort with the highest accuracy and specificity, which was 0.936 (95% CI 0.866~1.000) in the validation cohort. The AUC for the C model