Pestiviruses (family: Flaviviridae) are enveloped RNA viruses with highly variable single-stranded positive-sense RNA genomes of ∼12.3 kb that comprises a single large open reading frame (ORF) encoding a polyprotein of about 3,900 amino acids (aa) in length (Postel et al. 2015; Tautz et al. 2015). Some pestiviruses (e.g. bovine viral diarrhea virus, border disease virus, classical swine fever virus) are well-known animal pathogens that cause severe disease including contagious hemorrhagic disease in pigs and respiratory and reproductive disease in cattle and sheep (Vilcek and Nettleton 2006; Valdazo-Gonzalez et al. 2007; Moennig and Becher 2015). Wildlife disease (e.g. wild boar and deer) due to pestiviruses has also been reported (Ridpath et al. 2008; Blome et al. 2017). Following the application of molecular and genomics methods of virus discovery, a number of novel pestiviruses have been identified in recent years, including those from bats, rodents, and harbor porpoises (Wu et al. 2012; Firth et al. 2014; Smith et al. 2017; Jo et al. 2019). Finally, pestivirus-like viruses have also identified in arthropods (Shi et al. 2016a) and arthropods collected from mammals (Harvey et al. 2018). Together, these data highlight the circulation of a diverse range of pestiviruses in a broad range of animal hosts.