In this study, four pangolins—three M. javanica likely from Indonesia, Malaysia, and Thailand, and one M. pentadactyla probably of local origin—were found to be suffering disease and were sent to a local rescue station for treatment. Unfortunately, three animals died, whereas one recovered. To date, reports on pangolin disease have been rare and mainly limited to those caused by bacteria and parasites (Mohapatra et al. 2016; Jabin et al. 2019). There is no available literature on viral infections of pangolins until the recent identification of Parainfluenza Virus 5, sendai virus, and coronavirus from Sunda pangolins in China (Liu et al. 2019; Wang et al. 2019). Using a combination of meta-transcriptomic and PCR methods, we identified two novel RNA viruses—a pestivirus and a coltivirus—in two dead pangolins. Based on their clinical signs (Table 1), all these four pangolins appeared to suffer infectious disease. However, as no complete clinical data and laboratory parameters were obtained from these animals, we could not clearly define the disease they suffered.