FIGURE 2 Representative volcano plot analysis of gene expression of the interferon-stimulated genes (ISGs) in human bone marrow-derived mesenchymal stem (stromal) cells (BM-MSCs) activated with pro-inflammatory cytokines (interleukin-1β, tumour necrosis factor-α and interferon (IFN)-γ), versus control, in GEO dataset GSE68610. Gene expression analysis of a) constitutive and b) non-constitutive ISGs. ISG15: ubiquitin-like protein; CCL2: C-C motif chemokine 2; IFI6: IFN-α-inducible protein 6; PMAIP1: phorbol-12-myristate-13-acetate-induced protein 1; IFITM: IFN-induced transmembrane protein; CYP1B1: cytochrome p450 1b1; NPAS2: neuronal PAS domain-containing protein 2; TIMP-1: metalloproteinase inhibitor 1; MT1G/MT1X: metallothionein 1G/X; SERPING1: serpin family G member 1 (plasma protease C1 inhibitor); SAT1: sulfate anion transporter 1; GCA: grancalcin; IFNAR2: IFN-α/β receptor 2; SLC16A1: monocarboxylate transporter 1; ODC1: ornithine decarboxylase 1; FZD-5: Frizzled-5.