thogenic SARS-coronavirus 2 (SARS-CoV-2) is responsible for a global pandemic [1], and there is an urgent need to identify active antiviral agents. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay [2,3]. Several drugs have already been tested, among which chloroquine (CLQ), a well-known antimalarial drug, is one of the most promising