PMC:7127386 / 10809-11201 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"257","span":{"begin":136,"end":146},"obj":"Species"},{"id":"258","span":{"begin":69,"end":78},"obj":"Chemical"},{"id":"259","span":{"begin":245,"end":254},"obj":"Disease"},{"id":"260","span":{"begin":360,"end":368},"obj":"Disease"},{"id":"261","span":{"begin":156,"end":163},"obj":"CellLine"}],"attributes":[{"id":"A257","pred":"tao:has_database_id","subj":"257","obj":"Tax:2697049"},{"id":"A258","pred":"tao:has_database_id","subj":"258","obj":"MESH:D012254"},{"id":"A259","pred":"tao:has_database_id","subj":"259","obj":"MESH:D007239"},{"id":"A260","pred":"tao:has_database_id","subj":"260","obj":"MESH:D007239"},{"id":"A261","pred":"tao:has_database_id","subj":"261","obj":"CVCL:0574"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T33","span":{"begin":164,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T74","span":{"begin":136,"end":144},"obj":"Disease"},{"id":"T75","span":{"begin":245,"end":254},"obj":"Disease"}],"attributes":[{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T74","span":{"begin":147,"end":152},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T75","span":{"begin":156,"end":169},"obj":"http://purl.obolibrary.org/obo/CLO_0051719"},{"id":"T76","span":{"begin":235,"end":237},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T166","span":{"begin":69,"end":78},"obj":"Chemical"}],"attributes":[{"id":"A166","pred":"chebi_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/CHEBI_63580"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}

{"project":"LitCovid-sentences","denotations":[{"id":"T76","span":{"begin":108,"end":255},"obj":"Sentence"},{"id":"T77","span":{"begin":256,"end":392},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T263","span":{"begin":69,"end":78},"obj":"CHEBI:63580;DG_29;CHEBI:63580"},{"id":"T264","span":{"begin":136,"end":146},"obj":"SP_7"},{"id":"T265","span":{"begin":147,"end":152},"obj":"NCBITaxon:10239"},{"id":"T266","span":{"begin":156,"end":160},"obj":"NCBITaxon:10633;CL_6"},{"id":"T267","span":{"begin":208,"end":217},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T268","span":{"begin":288,"end":296},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T84655","span":{"begin":81,"end":85},"obj":"CL_6"},{"id":"T72639","span":{"begin":176,"end":185},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T69729","span":{"begin":197,"end":205},"obj":"CHEBI:31781;DG_23;CHEBI:31781"},{"id":"T75921","span":{"begin":226,"end":235},"obj":"DG_30"},{"id":"T18501","span":{"begin":268,"end":278},"obj":"CHEBI:37670;CHEBI:37670"},{"id":"T82311","span":{"begin":280,"end":288},"obj":"CHEBI:31781;DG_23;CHEBI:31781"},{"id":"T83691","span":{"begin":330,"end":339},"obj":"CHEBI:45409;DG_30;CHEBI:45409"}],"text":"Compounds were serially 2-fold or 4-fold diluted from 100 μM, except ribavirin which was started at 500 μM. Cytopathic effects (CPE) of SARS-CoV-2 virus in Vero E6 cells under increasing concentration of the compounds were observed at 48 h post-infection. The lowest concentration of the compound with 100% CPE inhibition (eg. exhibiting comparable CPE of non-infected controls) was recorded."}