Coronavirus Receptora May also bind Replication cycle inhibited by chloroquineb
Alphacoronavirus
 HCoV-229E Aminopeptidase N (APN)/CD13 Yes
 HCoV-NL63 Angiotensin-converting enzyme 2 (ACE2) ?
Heparan sulfate proteoglycansc
Betacoronavirus
 HCoV-OC43 HLA class Id, IFN-inducible transmembrane (IFITM) proteins in endocytic vesiclese Sialic acid (O-acetylated sialic acid)f Yes
 SARS-CoV-1 Angiotensin-converting enzyme 2 (ACE2) DC-SIGN/CD209, DC-SIGNr, DC-SIGN-related lectin LSECting Yes
 HCoV-HKU1 HLA class Ih Sialic acid (O-acetylated sialic acid) ?
 MERS-CoV i Dipeptidyl peptidase 4 (DPP4)/CD26 Yes
 SARS-CoV-2 ACE2i Sialic acid? Yes