Highlights • The novel coronavirus (2019-nCoV) pneumonia has caused 2033 confirmed cases, including 56 deaths in mainland China, by 2020-01-26 17:06. • We aim to estimate the basic reproduction number of 2019-nCoV in Wuhan, China using the exponential growth model method. • We estimated that the mean R 0 ranges from 2.24 to 3.58 with an 8-fold to 2-fold increase in the reporting rate. • Changes in reporting likely occurred and should be taken into account in the estimation of R 0.