Table 1 Neutralization activities of antisera from SARS-CoV and COVID-19 patients.
Patient serum SARS-CoV S pseudovirion SARS-CoV-2 S pseudovirion
SARS-CoV patient >80 40
COVID-19 patient #1 Not detected >80
COVID-19 patient #2 Not detected 40
COVID-19 patient #3 Not detected >80
COVID-19 patient #4 Not detected >80
COVID-19 patient #5 Not detected >80
SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file.