e glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV Abstract Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. Howeve