Pre-oxygenation should be carried out via a well-fitting face mask.25 Rapid sequence induction should be carried out to reduce the need for bag-mask ventilation.25 If bag-mask ventilation cannot be avoided, small tidal volumes (at low pressure) should be administered.25 Deep anesthesia and neuromuscular blockade should be achieved before attempting intubation, and the latter can be assessed by train-of-four monitoring. Ensure full expiration into the face mask before lifting it off the patient’s face. The most experienced operator should intubate.25 Following intubation, the cuff should be inflated and the circuit connected before initiating positive pressure ventilation. Closed, in-line tracheal suction should be used instead of open suction.33 Minimizing circuit disconnections is ideal, but if this is unavoidable, ensure positive pressure ventilation is ceased, turn the adjustable pressure limiting valve to zero, and consider clamping the endotracheal tube prior to disconnection. This technique may also be used before switching a patient from intensive care from the transport ventilator to the anesthetic machine. The patient should be preoxygenated and the duration of disconnection should be kept to a minimum to avoid exacerbating hypoxia in critically ill COVID-19 patients with respiratory failure.