What is the effect of the surface epitope and receptor binding domain of S protein of SARS-CoV-2 on the virus’ infectivity? Is there any effect of SARS-CoV vaccine designed according to S protein on SARS-CoV-2? Does SARS-CoV-2 orf8 and orf10 proteins, which have no homology proteins in SARS-CoV, play roles in the infectivity and pathogenicity of SARS-CoV-2? Can the susceptibility of asymptomatic carriers be judged by detecting the serum reactivity level of N protein? Apart from droplet transmission and contact transmission, are there other methods to transmit SARS-CoV-2? What is the percentage of COVID-19 patients have been infected with SARS and produced antibodies? Is there an effective specific anti-SARS-CoV-2 solution? Does traditional Chinese medicine have any effect on the treatment of COVID-19 caused by SARS-CoV-2? Do ethnic differences affect the transmissibility and pathogenicity of SARS-CoV-2? Do any environmental factors, such as regional conditions or climate, affect SARS-CoV-2 transmission?