GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7. GA was also reported to have activity against Escherichia coli and Staphylococcus aureus8. Several ways in which GA works have been suggested including by SUMOylation inhibition activity; blocking formation of the E1-SUMO intermediate9; inhibition of fatty acid synthase10; non-specific SIRT inhibition11; and activation of protein phosphatase type-2C12.