In this study, we are the first to report the fusion inhibitory effect of GA on enveloped viruses representing the three classes of fusion proteins and the inhibition of a non-enveloped human adenovirus. We also report a potential secondary mechanism of action involving viral DNA and protein synthesis. Our results are consistent with previous reports of the inhibitory effect of GA on DNA and protein synthesis22. The mechanism of action through which GA affects DNA and protein synthesis is not yet understood. It may bind to the host cell receptors and activate different cell signaling pathways and/or cause cell cycle arrest, which may explain the inhibitory effect of GA on rapidly dividing cancer cells. It may also enter the cells and work directly on DNA and protein synthesis. Experiments to address these questions are ongoing.