Ribavirin, a nucleoside analog, shows antiviral activity against some animal CoVs, and in the SARS-CoV epidemic, many patients were treated with ribavirin along with corticosteroids and became a standard regimen for the treatment of SARS-CoV. However, lack of control group hindered the estimation of true effect size. Again, in vitro testing did not show efficacy of ribavirin against SARS-CoV. Ribavirin is known for its side effects (hemolytic anemia, hypocalcemia, and hypomagnesemia). Many subsequent studies questioned the efficacy of ribavirin. Many patients on ribavirin and corticosteroid combination even showed an increase in viral load following the treatment. Thus, its use declined over a period.[8] Other important nucleoside analogs are favipiravir and galidesivir, but these are not evaluated till now in 2019-nCoV.