What measures are likely to be successful in curbing its further spread? On January 23rd, Hubei province in Central China was locked down with all movement in and out of the province blocked. Travel across China was discouraged and the number of scheduled flights and train journeys available considerably reduced to perhaps 10% of previous activity. Commercial and social activities became negligible, with schools, restaurants, other entertainment spots and most shops closed. Migrant workers were prevented from returning to work after the extended Chinese New Year Holiday. Frequent hand hygiene when in public and staying at home became the norm. This unprecedented public health effort by China has afforded the rest China and the world a lead time to prepare. The lockdown resulted in a downward trend in national and provincial epidemic curves, however, these measures are not sustainable and eventually there will be a strategy to return to normality. Should this result in a second wave of cases, and more international spread, countries around the world must be prepared. Early identification, and isolation or cohorting of positive cases to designated sites is at the core. In order to achieve this, hospitals, quarantine services, laboratories, together with epidemiology and communication teams will need to be scaled up to provide effective and efficient care.