Upper respiratory tract (URT) and lower respiratory specimen (LRT) specimens were collected from confirmed patients every day after the diagnosis of SARS-CoV-2 infection and sent to Korea Center for Disease Control for follow-up tests and culture. Nasopharyngeal and oropharyngeal swabs were collected and placed in the same tube as URT specimen, and sputum was used as LRT specimen.5 Serum, plasma, urine, and stool samples were also collected sequentially during the illness. Real-time reverse transcriptase polymerase chain reaction (rRT-PCR) was used to detect SARS-CoV-2 using the published sequences.6 The cycle threshold (Ct) values of rRT-PCR was converted into RNA copy number of SARS-CoV-2. The detection limit of quantitative PCR reaction was 2,690 copies/mL. Detailed methods and values for the tests are presented in the Supplementary Data 1 and Supplementary Tables 1 to 3.