There are also limitations in our report. Since we only presented two patients (mild and moderate), the information from these patients may not be generalizable to many other cases, especially severe cases. Second, Lopinavir/ritonavir was used in both patients on day 5 and day 17 from symptom onset, but its role cannot be determined in viral load reduction or clinical improvement. In addition, since they received Lopinavir/ritonavir which can also cause diarrhea, how much of gastrointestinal tract symptom was in fact related to SARS-CoV-2 or drug side effect. Third, we cannot estimate the time point when these patients were exposed to virus and when they started to shed the virus from their respiratory secretions. These data are also urgently needed to understand this virus better and to implement the control strategies as early as possible. Finally, the virus has not been readily cultured from these specimens, yet, although we are still trying. It is not clear whether there was not viable virus (possibly infectious) or we were not successful to culture this newly discovered virus in the beginning. Therefore, knowing the virus load that can give a positive culture result is important in the future. There is scarce information on viral load kinetics in SARS-CoV-2 infected patients throughout the illness. Therefore, although our report is based on observation from only two patients, this will provide valuable insight to understand the nature of this virus.