Blocking transmission Learning from the SARS outbreak, which started as animal-to-human transmission during the first phase of the epidemic, all game meat trades should be terminate to prevent this portal of transmission. At the same time, we could not ignore the environmental assessments at the seafood market and investigations to identify the pathogen causing the outbreak. Person-to-person transmission was efficient and super-spreading events had led to major outbreaks in public gathering places. The severity of disease is an important indirect factor helps to identify those who had been infected. If infection does not cause serious disease or asymptomatic infection, infected people probably end up in health care centers. Instead, they would go to work and travel, thereby potentially spreading the virus to their contacts [16]. Recent epidemiological survey and studies showed the patients who did not travel to Wuhan became infected with the virus after several days of contact with the family members. None of the family members had contacts with Wuhan markets or animals, neither had visited a Wuhan hospital [21]. Person-to-person transmission in family homes or hospital, and intercity spread of 2019-nCoV are occurring, and therefore vigilant control measures are warranted at the whole stage of the epidemic.