Case 2 was a 31-year-old Chinese male tourist who had left Wuhan on 18 January and arrived in Paris on 19 January. He developed fever, chills, fatigue, conjunctivitis and cough on 19 January. Case 3 was a 30-year-old Chinese female tourist who travelled with Case 2. She developed fever, chills, fatigue and cough on 23 January. On 24 January, they were advised by the Chinese embassy to seek medical attention at the national hotline (SAMU-centre 15) and were immediately transferred to a regional referring hospital, isolated and sampled for laboratory confirmation of COVID-19. Infection with SARS-CoV-2 was confirmed on 24 January for both of them by the National Reference Centre (Figure). Cases 2 and 3 were positive by RT-PCR for all targets of the Charité procedure [4] (RdRp Pan Sarbeco and 2019-nCov probes; E; N) as well for the four RdRp-IP targets with Ct values in good agreement with those obtained for the E gene target.