Case 1 was a 48-year-old male patient living in France. He was travelling for professional reasons in China in various cities including Wuhan when he experienced his first symptoms (fever, headaches and cough) on 16 January. He flew back to Bordeaux, France on 22 January via Shanghai, Qingdao and Paris Charles de Gaulle airports. He reported wearing a mask during the flights. He sought medical attention from a general practitioner on 23 January, where he was suspected of COVID-19, and was subsequently transferred to the regional referring hospital in Bordeaux, isolated and sampled for laboratory confirmation of SARS-CoV-2 infection. Infection was confirmed on 24 January by the National Reference Centre (Figure). Case 1 tested positive only for the E gene target when using the Charité procedure [4] and was positive for all four RdRp-IP targets with threshold cycles (Ct) in good agreement with those obtained for the E gene target.