PMC:7019868 / 36612-37534 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"719","span":{"begin":206,"end":214},"obj":"Disease"},{"id":"722","span":{"begin":592,"end":600},"obj":"Disease"},{"id":"723","span":{"begin":709,"end":720},"obj":"Disease"}],"attributes":[{"id":"A719","pred":"tao:has_database_id","subj":"719","obj":"MESH:D003967"},{"id":"A722","pred":"tao:has_database_id","subj":"722","obj":"MESH:D003967"},{"id":"A723","pred":"tao:has_database_id","subj":"723","obj":"MESH:D015430"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T178","span":{"begin":648,"end":654},"obj":"Body_part"}],"attributes":[{"id":"A178","pred":"fma_id","subj":"T178","obj":"http://purl.org/sig/ont/fma/fma64183"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T37","span":{"begin":648,"end":654},"obj":"Body_part"}],"attributes":[{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0001988"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T40","span":{"begin":206,"end":214},"obj":"Disease"},{"id":"T41","span":{"begin":592,"end":600},"obj":"Disease"},{"id":"T42","span":{"begin":642,"end":654},"obj":"Disease"}],"attributes":[{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T420","span":{"begin":95,"end":102},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T421","span":{"begin":347,"end":350},"obj":"http://purl.obolibrary.org/obo/CLO_0053799"},{"id":"T422","span":{"begin":902,"end":910},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T186","span":{"begin":555,"end":557},"obj":"Chemical"},{"id":"T187","span":{"begin":559,"end":561},"obj":"Chemical"},{"id":"T188","span":{"begin":563,"end":565},"obj":"Chemical"}],"attributes":[{"id":"A186","pred":"chebi_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/CHEBI_73419"},{"id":"A187","pred":"chebi_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/CHEBI_73419"},{"id":"A188","pred":"chebi_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/CHEBI_73419"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T85","span":{"begin":136,"end":150},"obj":"http://purl.obolibrary.org/obo/GO_0019076"},{"id":"T86","span":{"begin":163,"end":177},"obj":"http://purl.obolibrary.org/obo/GO_0019076"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-sentences","denotations":[{"id":"T259","span":{"begin":0,"end":103},"obj":"Sentence"},{"id":"T260","span":{"begin":104,"end":256},"obj":"Sentence"},{"id":"T261","span":{"begin":257,"end":324},"obj":"Sentence"},{"id":"T262","span":{"begin":325,"end":396},"obj":"Sentence"},{"id":"T263","span":{"begin":397,"end":467},"obj":"Sentence"},{"id":"T264","span":{"begin":468,"end":537},"obj":"Sentence"},{"id":"T265","span":{"begin":538,"end":580},"obj":"Sentence"},{"id":"T266","span":{"begin":581,"end":922},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T29","span":{"begin":206,"end":214},"obj":"Phenotype"},{"id":"T30","span":{"begin":243,"end":254},"obj":"Phenotype"},{"id":"T31","span":{"begin":592,"end":600},"obj":"Phenotype"},{"id":"T32","span":{"begin":709,"end":720},"obj":"Phenotype"},{"id":"T33","span":{"begin":754,"end":767},"obj":"Phenotype"}],"attributes":[{"id":"A29","pred":"hp_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A30","pred":"hp_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/HP_0004324"},{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0004324"},{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0004324"}],"text":"Table 2 Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.\nGroup Mortality Rate (%) Peak Viral Shedding (DPI) Peak Viral Shedding (log10 copies/mL) Onset of Diarrhea (DPI) † Mean Average Daily Weight Gain ‡\niPEDVPT-P5 87.5 (7/8) 1 10.06 ± 1.14 1.00 ± 0.0 −0.116 ± 0.135\niPEDVPT-P5-96S 80.0 (4/5) 7 9.15 ± 0/91 3.83 ± 1.47 −0.033 ± 0.062\niPEDVPT-P96-5S 83.4 (5/6) 1 8.20 ± 1.70 1.00 ± 0.0 −0.035 ± 0.049\niPEDVPT-P96 40.0 (2/5) 10 9.74 ± 0.74 2.38 ± 1.51 −0.016 ± 0.055\nMock 0.0 (4/4) ND ND ND 0.051 ± 0.016\n† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized."}