Table 2  Summary of clinical observations used for evaluating the pathogenicity of recombinant viruses.
Group  Mortality Rate (%)  Peak Viral Shedding (DPI)  Peak Viral Shedding (log10 copies/mL)  Onset of Diarrhea (DPI) †  Mean Average Daily Weight Gain ‡
iPEDVPT-P5  87.5 (7/8)  1  10.06 ± 1.14  1.00 ± 0.0  −0.116 ± 0.135
iPEDVPT-P5-96S  80.0 (4/5)  7  9.15 ± 0/91  3.83 ± 1.47  −0.033 ± 0.062
iPEDVPT-P96-5S  83.4 (5/6)  1  8.20 ± 1.70  1.00 ± 0.0  −0.035 ± 0.049
iPEDVPT-P96  40.0 (2/5)  10  9.74 ± 0.74  2.38 ± 1.51  −0.016 ± 0.055
Mock  0.0 (4/4)  ND  ND  ND  0.051 ± 0.016
† Onset of diarrhea was defined as day post-inoculation when loose stools scored as two or above were recorded. ‡ Average daily weight gain (AVG) was calculated by dividing weight gained by survival days; mean value was calculated as dividing the sum of AVG by the number of piglets in the indicated groups that were not humanely euthanized.