PMC:7019868 / 18951-19611 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T92","span":{"begin":133,"end":138},"obj":"Body_part"},{"id":"T93","span":{"begin":276,"end":280},"obj":"Body_part"},{"id":"T94","span":{"begin":509,"end":513},"obj":"Body_part"},{"id":"T95","span":{"begin":619,"end":623},"obj":"Body_part"}],"attributes":[{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"The in vitro characteristics of the recombinant viruses were compared by evaluation of the size of syncytia, growth kinetics in Vero cells, and plaque morphologies. All recombinant viruses induced formation of syncytia by 18 h post-infection. Viruses carrying the identical S gene exhibited similar fusogenic ability as suggested by the comparable number of nuclei per syncytium; representative micrographs used to count the number of nuclei in syncytia are shown in Figure 1A. Remarkably, viruses carrying S gene derived from iPEDVPT-P96, induced 3.5 to 4 times larger syncytia than the other two viruses containing S gene derived from iPEDVPT-P5 (Figure 1B)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T20","span":{"begin":232,"end":241},"obj":"Disease"}],"attributes":[{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"The in vitro characteristics of the recombinant viruses were compared by evaluation of the size of syncytia, growth kinetics in Vero cells, and plaque morphologies. All recombinant viruses induced formation of syncytia by 18 h post-infection. Viruses carrying the identical S gene exhibited similar fusogenic ability as suggested by the comparable number of nuclei per syncytium; representative micrographs used to count the number of nuclei in syncytia are shown in Figure 1A. Remarkably, viruses carrying S gene derived from iPEDVPT-P96, induced 3.5 to 4 times larger syncytia than the other two viruses containing S gene derived from iPEDVPT-P5 (Figure 1B)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T195","span":{"begin":48,"end":55},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T196","span":{"begin":128,"end":132},"obj":"http://purl.obolibrary.org/obo/CLO_0009524"},{"id":"T197","span":{"begin":128,"end":132},"obj":"http://purl.obolibrary.org/obo/CLO_0050515"},{"id":"T198","span":{"begin":133,"end":138},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T199","span":{"begin":181,"end":188},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T200","span":{"begin":222,"end":224},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T201","span":{"begin":243,"end":250},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T202","span":{"begin":276,"end":280},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T203","span":{"begin":369,"end":378},"obj":"http://purl.obolibrary.org/obo/CL_0000228"},{"id":"T204","span":{"begin":490,"end":497},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T205","span":{"begin":509,"end":513},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T206","span":{"begin":598,"end":605},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T207","span":{"begin":619,"end":623},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"}],"text":"The in vitro characteristics of the recombinant viruses were compared by evaluation of the size of syncytia, growth kinetics in Vero cells, and plaque morphologies. All recombinant viruses induced formation of syncytia by 18 h post-infection. Viruses carrying the identical S gene exhibited similar fusogenic ability as suggested by the comparable number of nuclei per syncytium; representative micrographs used to count the number of nuclei in syncytia are shown in Figure 1A. Remarkably, viruses carrying S gene derived from iPEDVPT-P96, induced 3.5 to 4 times larger syncytia than the other two viruses containing S gene derived from iPEDVPT-P5 (Figure 1B)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T105","span":{"begin":358,"end":364},"obj":"Chemical"},{"id":"T106","span":{"begin":435,"end":441},"obj":"Chemical"}],"attributes":[{"id":"A105","pred":"chebi_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A106","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"}],"text":"The in vitro characteristics of the recombinant viruses were compared by evaluation of the size of syncytia, growth kinetics in Vero cells, and plaque morphologies. All recombinant viruses induced formation of syncytia by 18 h post-infection. Viruses carrying the identical S gene exhibited similar fusogenic ability as suggested by the comparable number of nuclei per syncytium; representative micrographs used to count the number of nuclei in syncytia are shown in Figure 1A. Remarkably, viruses carrying S gene derived from iPEDVPT-P96, induced 3.5 to 4 times larger syncytia than the other two viruses containing S gene derived from iPEDVPT-P5 (Figure 1B)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T39","span":{"begin":109,"end":115},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T40","span":{"begin":197,"end":206},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"The in vitro characteristics of the recombinant viruses were compared by evaluation of the size of syncytia, growth kinetics in Vero cells, and plaque morphologies. All recombinant viruses induced formation of syncytia by 18 h post-infection. Viruses carrying the identical S gene exhibited similar fusogenic ability as suggested by the comparable number of nuclei per syncytium; representative micrographs used to count the number of nuclei in syncytia are shown in Figure 1A. Remarkably, viruses carrying S gene derived from iPEDVPT-P96, induced 3.5 to 4 times larger syncytia than the other two viruses containing S gene derived from iPEDVPT-P5 (Figure 1B)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T140","span":{"begin":0,"end":164},"obj":"Sentence"},{"id":"T141","span":{"begin":165,"end":242},"obj":"Sentence"},{"id":"T142","span":{"begin":243,"end":477},"obj":"Sentence"},{"id":"T143","span":{"begin":478,"end":660},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The in vitro characteristics of the recombinant viruses were compared by evaluation of the size of syncytia, growth kinetics in Vero cells, and plaque morphologies. All recombinant viruses induced formation of syncytia by 18 h post-infection. Viruses carrying the identical S gene exhibited similar fusogenic ability as suggested by the comparable number of nuclei per syncytium; representative micrographs used to count the number of nuclei in syncytia are shown in Figure 1A. Remarkably, viruses carrying S gene derived from iPEDVPT-P96, induced 3.5 to 4 times larger syncytia than the other two viruses containing S gene derived from iPEDVPT-P5 (Figure 1B)."}