Table 1  Parameters describing organ function and systemic inflammation in sham-operated animals with and without MSC administration.
Parameter   Timepoint   CONTROL   MSC-CONTROL
Urea (mmol/L)  Baseline  5 (4.2–5.5)  5.7 (5–6.6)
+12 H  5.5 (3.6–5.9)  6.1 (5.1–7.3)*
+18 H  5 (3.3–5.6)  5.5 (4.5–6.6)
+24 H  4.4 (3.2–4.6)  4.7 (3.8–5.8)*
Creatinine (μmol/L)  Baseline  95 (80–103)  99 (87–110)
+12 H  93 (77–108)  100 (88–107)
+18 H  88 (77–102)  95 (86–102)
+24 H  85 (68–93)  89 (83–103)
AST (μkat/L)  Baseline  0.7 (0.6–1.5)  0.8 (0.6–1.9)
+12 H  0.8 (0.7–1.4)  0.9 (0.8–1.1)
+18 H  0.8 (0.7–1.6)  1.0 (0.9–1.5)
+24 H  0.8 (0.7–1.4)  1.0 (0.9–1.4)
ALT (μkat/L)  Baseline  0.5 (0.5–0.7)  0.6 (0.5–0.7)
+12 H  0.5 (0.5–0.6)  0.5 (0.48–0.51)*
+18 H  0.5 (0.4–0.6)  0.5 (0.47–0.50)*
+24 H  0.5 (0.4–0.5)*  0.52 (0.5–0.5)*
Trombocytes (1 × 109/L)  Baseline  285 (226–315)  260 (231–357)
+12 H  227 (204–302)  200 (191–236)*
+18 H  236 (213–271)  201 (164–220)*
+24 H  241 (216–252)  194 (190–226)*
PaO2/FiO2 (mmHg)  Baseline  459 (410–510)  450 (441–466)
+12 H  408 (399–460)  452 (410–455)
+18 H  344 (262–404)*  355 (327–414)*
+24 H  272 (232–353)*  313 (187–412)*
hsTnT (ng/L)  Baseline  7.2 (6.2–18.1)  9.7 (7.4–36.3)
+12 H  7.7 (6.7–21.6)  9.2 (7.6–24.8)
+18 H  6.1 (5.6–17.4)*  9 (7.1–19.9)
+24 H  5.9 (4.5–17.8)*  10.5 (6.6–18.7)
IL-6 (ng/L)  Baseline  47 (36–75)  59 (47–114)
+12 H  48 (30–63)  38 (16–64)
+18 H  64 (48–212)  61 (33–66)
+24 H  352 (139–1,451)*  175 (35–768)
TNF-α (ng/L)  Baseline  91.3 (77.7–123.2)  100.3 (62.1–145.1)
+12 H  58.9 (54.2–89.5)  52.7 (38.8–75.8)*
+18 H  60.0 (53.4–68.5)  59.3 (50.7–88.9)*
+24 H  76.5 (61.5–119.3)  94.2 (57.4–112.2)
8-Isoprostane (μg/L)  Baseline  32.0 (4.9–55.8)  43.3 (23.0–93.2)
+12 H  8.4 (6.7–28.5)  23.5 (11.6–31.3)
+18 H  5.7 (4.9–14.1)  15.1 (4.0–37.1)
+24 H  6.7 (4–72.3)  55.6 (14.1–89.4)
AST, aspartate aminotransferase; ALT, alanine aminotransferase; PaO2/FiO2, oxygenation index; hsTnT, high-sensitivity troponin T; IL-6, interleukin 6; TNF-α, tumor necrosis factor α.
*  p < 0.05 between baseline and time-point. No statistical significance was found between groups.