Funding
This study was supported by the São Paulo Research Foundation (FAPESP; grant 2012/51316-5 to D.S.P.A.) and the National Council for Scientific and Technological Development (CNPq; grant 573663/2008-4 to National Institute of Science and Technology for Pharmaceutical Innovation-INCT_if/CNPq). T.d.E.S.F., S.M.K., M.F.C. and J.M.S. were supported by scholarships from FAPESP. G.L.T. was supported by a scholarship from CNPq. M.F.S.D. was supported by a scholarship from CAPES. C.L.P.O. acknowledges support from FAPESP and CNPq.