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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6723065","sourcedb":"PMC","sourceid":"6723065","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6723065","text":"2.1.5. Impulse Control Disorder\nImpulse Control Disorder (ICD) (i.e., hypersexuality, gambling, binge-eating, compulsive shopping or hobbying, punding, and homeostatic hedonism disorders) are more frequent in young, male patients [71]. ICD main risk factors include dopaminergic replacement therapy, in particular with DAs (14%–17% of cases), and disease duration [72,73]. In these patients, DA therapy should be discontinued (or at least reduced until ICD cessation) with proportional l-dopa dose adjustment. However, some patients could experience DAWS, with mood, autonomic, and sleep disorders, requiring careful symptomatic management [72].\nOther NMS, which can appear in the early stage but are prominent during the progression of disease, will be later discussed.","divisions":[{"label":"title","span":{"begin":0,"end":31}},{"label":"p","span":{"begin":32,"end":645}}],"tracks":[{"project":"2_test","denotations":[{"id":"31434341-30361297-7278273","span":{"begin":231,"end":233},"obj":"30361297"},{"id":"31434341-29872418-7278274","span":{"begin":365,"end":367},"obj":"29872418"},{"id":"31434341-22933817-7278275","span":{"begin":368,"end":370},"obj":"22933817"},{"id":"31434341-29872418-7278276","span":{"begin":641,"end":643},"obj":"29872418"}],"attributes":[{"subj":"31434341-30361297-7278273","pred":"source","obj":"2_test"},{"subj":"31434341-29872418-7278274","pred":"source","obj":"2_test"},{"subj":"31434341-22933817-7278275","pred":"source","obj":"2_test"},{"subj":"31434341-29872418-7278276","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ecc8","default":true}]}]}}