Preimplant major stroke is present in 3.6% of the patients in the INTERMACS Registry; other cerebrovascular diseases are present in 3.8%. Neurological and cognitive function should be assessed before LT-MCS implantation [104]. No worldwide accepted psychosocial assessment is available. The Stanford Integrated Psychosocial Assessment for Transplant can, however, certainly be used for LT-MCS candidates [105, 106].