Recommendations for aortic insufficiency Recommendations Class Level References Diagnosis Echocardiography for routine follow-up of aortic valve function is recommended. I C [460, 462] The ramp test to diagnose aortic insufficiency should be considered. IIa C [463] Treatment of moderate aortic insufficiency Variation in pump speed settings to reduce aortic insufficiency should be considered. IIa B [68] A heart transplant is recommended. I C Open valve replacement or closure of an insufficient aortic valve is not recommended. III C Interventional closure of the aortic valve may be considered. IIb C [458, 461, 464] Transcatheter aortic valve replacement should be considered. IIa C [461, 465, 466] Treatment of severe aortic insufficiency Reduction in pump speed settings to reduce aortic insufficiency may be considered. IIb C [68] High-urgent listing for a heart transplant is recommended if the patient is a transplant candidate. I C Open valve replacement or closure of the insufficient aortic valve may be considered. IIb C [457, 467] Interventional closure of the aortic valve may be considered. IIb C [458, 461, 464] Transcatheter aortic valve replacement should be considered. IIa C [461, 465, 466]