CVAs are described for all types of devices, and the reported incidences with modern devices remain high [145]. Overall incidence ranges from 6.7% to 29.7% (0.07 to more than 0.26 events per patient year). BP management is of primary importance: mean arterial pressure higher than 90 mmHg is associated with a risk of stroke during CF-LVAD support [146, 433]. Doppler BP measurement is the gold standard, and it reflects systolic BP. Antiplatelet and antithrombotic therapies are crucial as prophylaxis against CVA: Use of aspirin and strict anticoagulation monitoring are protective for CVA.