Chemotherapy & CD39 inhibition ➣ Chemotherapy: Mitoxantrone (406) Oxaliplatin (406) ➣ CD39 pharmacologic inhibitor: ARL67156 (406) ➣ Colon: CT26 (406) ➣ Fibrosarcoma: MCA205 (406) ➣ Primary tumor expansion rate ↓ (406) T cells (406) Knockdown of tumor Atg5 (406) ↑ Extracellular ATP (406)↑ DCs (406)↑ IFN-γ+ CD4+, CD8+ T cells (406)↑ IL-17A+ γδ T cells (406)↑ IFN-γ (406)