Survival rates in trials and registry reports of heart transplantation and chronic mechanical circulatory support as DT. Reprinted with permission from Ref. [48]. DT: lifetime therapy; HM: HeartMate; LVAD: left ventricular assist device; OMM: optimal medical management; VE/XVE: early generation ventricular assist devices (HeartMate VE/XVE, Thoratec Corp., Pleasanton, CA).