In all, here we demonstrate handedness modulates drift within hands (spatial modulation of drift) as well as between hands (difference between dominant and non-dominant hands). Future work will be required to disambiguate usage-based, visual expectation/ cognitive and potential possible laterality-based (see “Introduction”) contributions to these handedness-based drift effects. Ideally, training protocols of new or extreme spatial action patterns may provide causal evidence of the relationship we propose here.