Figure 6 Distal Ciliary Axonemes of DNAH9-Deficient Respiratory Cells Display Subtle Ultrastructural Defects of the Outer Dynein Arms (ODAs)
(A and B) Loss-of-function mutations in DNAH9 cause distal absence of ODAs in the transmission-electron microscopy but do not affect the ODA docking complex (DC) (red arrow in A).
(C and D) Interestingly, ODAs in the proximal part of the ciliary axonemes (blue arrow in C) are not affected by DNAH9 deficiency. The green arrow in (D) marks microvilli extending from the apical side of the cell.
Scale bars represent 200 nm. A total of 153 ciliary cross-sections were analyzed.