The scientific study of connectomics involves mapping out the detailed connectivity of brain regions to characterize the architectural networks of the human brain. Connectomics is therefore a powerful tool to visualize the structural and functional dysconnections associated with schizophrenia. The human connectome provides a detailed map of brain-wide circuit connectivity and allows inference into how brain function may be affected by disruption of the structural organizational network (31, 34). At the micro-scale, the physical wiring of single neurons and their synaptic connections to other neurons through dendritic and axonal connections comprise local network circuits. At the meso-scale (local populations of 80–100 neurons that span all cortical layers), connectivity is at the level of functionally specialized subnetworks within single cortical columns that are selectively connected within and between neighboring cortical columns and constitute a major functional element for cortical information processing. At the macro-scale, inter-regional connectivity of cerebral lobes via WM interhemispheric tracts is responsible for the integration and relay of information between various parts of the brain (34).