(B) A bar plot of the percentage of DNA-methylation sites associated with common genetic variation and grouped by previous reported estimates of heritability (percent variation in DNAm is explained by additive genetic factors taken from van Dongen et al.13). Each bar plot demonstrates the percentage of DNA-methylation sites with Bonferroni significant genetic effects in cis only (blue), trans only (green), and both cis and trans (red) and with no significant genetic effects (white).