(A) The genomic distribution of Bonferroni-significant (p = 6.52 × 10−14) mQTLs in whole blood; the position on the x axis indicates the location of Illumina EPIC array probes, and the position on the y axis indicates the location of genetic variants. The color of the point corresponds to the difference in DNA methylation per allele compared to the reference allele; the largest effects are plotted in dark red. A clear positive diagonal can be observed, demonstrating that the majority of mQTLs are associated with genotype in cis.