Figure 4 Variation Rate for Deafness-Associated Genes (A) Total number of variants per gene. (B) Normalized number of coding variants based on the size of the coding and splice regions. (C) Normalized number of deafness-associated variants (P+LP) based on the total number of coding variants. Only genes with ≥14 reported deafness-associated variants are included in this figure; the remaining genes are shown in Figures S2 and S3.