(74)  Type I diabetes mellitus  Adipose tissue  Administration of adipose tissue-derived MSCs overexpressing betatrophin Administration of adipose tissue-derived MSCs alone  Mice  ↓Hyperglycemia↓Weight loss Effectiveness of adipose tissue-derived MSCs overexpressing betatrophin > Effectiveness of adipose tissue-derived MSCs alone  ↑Islet proliferation↑Ngn3 transcription factor↑Pax6 transcription factor↑Islet production of insulin↑β-cells ratio↑IL-4↑IL-10↑IL-13↓TNF-α↓NADP-cytochrome P450 reductase↑XIAP in the islets↑Bcl-xL in the islets↑Bcl-2 in the islets↓Caspase-3 in the islets↓Apoptotic cells