References   Autoimmune disease   Source of hMSC   Variables   Experimental model   Clinical and laboratory effects   Mechanism proposed
(119)  Idiopathic pulmonary fibrosis  Bone marrow Umbilical cord  None  Mice  ↑Survival rates↓Pulmonary inflammation and fibrosis Effectiveness bone marrow-derived MSCs > effectiveness umbilical cord-derived MSCs  ↓CD3+CD56+ NKT cells↓CD3+CD8+ T cell induction↑CD3+CD4+ T cells↑CD4+CD25+CD127(low/−)/foxp3+ Tregs↓IFN-γ↓TNF-α↓IL-6↓IL-8↓CCL2↓α-SMA activation↑TGF-β1↑CXCL10
(120)  Idiopathic pulmonary fibrosis  Adipose tissue  None  Mice  ↑Survival rates↓Ashcroft's modified score for lung fibrosis↓Lung weight↓Lung pathology↓Collagen deposition in the lungs  ↓IL-2↓IL-1β↓TNF-α↓TGF-β↓bFGF↓CTGF↓COL3a1↓CoL1a1↓Matrix metalloproteinases↓Tissue inhibitor of metalloproteinases