Variant filters applied to annotated VCF files produced 89 unique variants in 119 individuals for further ACMG-guideline-based assessment. Of these, 22 (42 occurrences) could be classified as pathogenic, 23 (24 occurrences) could be classified as likely pathogenic, 24 (27 occurrences) could be classified as a variant of uncertain significance (VUS), and 20 (26 occurrences) could be classified as likely benign. Six occurrences of P/LP variants occurred in two members of the same family, and only three of these contributed to the detection rates quoted below. No pathogenic non-coding variants were identified.