GWAS Signature for IREB2 Co-localizes with the Conditional eQTL Signature
(A) P-P plots comparing −log10 p values from GWAS (y axes) and all-but-one conditional eQTL analysis (x axes), which show the highest correlation to be between the GWAS and the conditional eQTL rs7171869 (blue, bottom).
(B) LocusZoom plots for the IREB2 locus, where the GWAS signal (top) more closely resembles the conditional eQTL signal (rs7171869, bottom) than the primary eQTL signal (rs11639224, third from top) or non-conditional eQTL signal (second from top). For all LocusZoom plots, LD is colored with respect to the GWAS lead SNP (rs8042374, labeled).