Acknowledgements
We acknowledge the patients, GPs, paediatricians and the nurse who participated in this study as well as the contribution of Jesús Almeda, Rosa Morros, Rosa Juvé, Pere Simonet, Laura Prats and Edurne Zabaleta in developing the project. We would also like to thank Francois Schellevis, Mike Pringle, Ellen Stobberingh, Herman Goossens and Gilles Hebbrecht who conducted and coordinated the APRES project and Samuel Coenen for his contribution to the protocol.
List of physicians and nurse participating in this study: Guinardó Primary Care Centre, Barcelona: M. Carme Casanovas Fuste, Jordi Nadal Echevarría, Antonia Herrera Ruiz, M. Asunción Altaba Barceló, Albert Boada Valmaseda. Congrés Primary Care Centre, Barcelona: Natalia López Pareja, M. Ángeles Salvador Millán. Santa Eulàlia Sud,Primary Care Centre L’Hospitalet del Llobregat: Xavier Mas Garriga, Isabel Zamora Casas, Immaculada Cid, Francisco Javier Cañamares Barroso. Viladecans 2 Primary Care Centre, Viladecans: Pere J. Simonet Aineto, Rosa Villafáfila Ferrero, Noelia Esplugas Muñoz, Estefania Sanjuán Sanchís, M. Jesús Llobera Bauza, Concepció García Peláez. Corbera Primary Acre Centre, Corbera de Llobregat: Luis Altmann Muller, Ana M. Embid García. La Gavarra Primary Care Centre, Cornellà del Llobregat: Marta Soler Costa, Jordi Argimon Font, Raquel Martos Medina. Sant Ildefons Primary Care Centre, Cornellà del Llobregat: Manuel Álvarez Fernández, Marta Rosario D'Lacoste Farre, Eulalia Ruiz Gil, Amparo Pallarés Sancho-Tello, Josep Balaguer Martínez.
This work has been carried out under the doctorate programme of the Universitat Autònoma de Barcelona of the doctoral student Albert Boada Valmaseda

Disclosure statement
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.