The second question concerned the resection status. To make this feasible for the study, we did it like others before. We only took patients with pathologically confirmed complete resections. So when the pathologist stated in one of the multiple centres, in Canada, Italy, Austria, that this was a complete resection, then we took this for the analysis of freedom from recurrence. We did not include patients who had incomplete resection after R1 resection, and who may have had a complete remission after postoperative therapy, in the analysis of freedom from recurrence. We wanted to have this as clean as possible, so we only took the pathologically confirmed complete resections in this study. We thought this would be the cleanest approach.