The ESC/EACTS guidelines suggest that in view of the higher risk of procedural mortality with redo-CABG and the similar long-term outcome, percutaneous coronary intervention is the preferred revascularization strategy in CABG patients requiring redo revascularization [26]. The findings of our Matched Analysis B suggests an overall in-hospital mortality of 2.5% (0% for redo-OPCAB) and 1-, 5-, and 10-year survival rates of 96, 88 and 71.6%, respectively. These remarkable results question the rationale of treating these patients with percutaneous coronary intervention stenting [5] and call for a more in-depth evaluation of the available evidence.